Research Goals

The primary goal of our research is to elucidate the molecular mechanism of function of various proteins and to understand the structural basis for their biological activity. A variety of research tools including single crystal X-ray crystallography are employed. A significant amount of research effort is devoted to the study of proteins from infectious organisms. Infectious diseases are still the leading cause of death worldwide. Long known infections such as malaria, tuberculosis, diarrhea are still at the top of the list of killer diseases. Rapid emergence of resistance to drugs emphasizes the need for continuous research to identify novel targets in the microbes for developing effective drugs.

Research Programs

• Malaria
• Trafficking
• Chagas Disease
• Structural Biology of Pathogenic Parasites
• Structure of Bacterial Surface Proteins & Receptors
• Structural Biology of Emerging Pathogens of Biodefense Significance

Graduate Studies

• Cellular & Molecular Biology
• Biochemistry & Molecular Genetics
• Physiology & Biophysics
• Microbiology
• Medical Scientist training program

Other Lab Information

• Technical Capabilities, Resources, & Research Opportunities
• Research Team
• Collaborations
• Recent Publications
• Contact Information